Whitechapel is the small town where Sarah, Ethan and Benny resides in. Austin and Ally will also stay here for a while during their three-year school exchange program. The town is a hotspot for all kinds of supernatural activity like Zombies, Vampires and Witches. The town was originally called Black's Church after Reverend Black (currently known by his alias of Jesse), was a vampire with a following responsibility for the murders of many early townspeople. Soon, this eventually caused them to all revolt, for which they mobbed together in the gruesome burning of Black and his followers, believing to have killed them all. Free of their evil reverend, the victorious town was later named Whitechapel.
Whitechapel is known to be in the Canadian province of Ontario based on the license plates of local residents' cars, although the setting is never specified outright. Given its' founding in 1809, it is most likely along the coast of Lake Ontario, either in the Greater Toronto Area or the more rural north shore of the lake, as those were the main areas settled prior to the War of 1812.